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Principal Research Associate/Scientist, Analytical Development

eGenesisCambridge, Massachussets, United StatesOnsite
This job is no longer open

COMPANY MISSION


At eGenesis, we aspire to deliver safe and effective human transplantable cells, tissue and organs utilizing the latest advancements in genome editing. 

POSITION SUMMARY


We are seeking a highly motivated individual to join the Analytical Development team as a Principal Research Associate/Scientist. This position is an excellent opportunity to help develop new gene editing and xenotransplantation products in an exciting and dynamic environment focused on cutting-edge molecular and cellular engineering technology.In this role, you will lead a small team responsible for developing and qualifying methods to assess transgene expression and function in genetically modified porcine cells.

This role will involve significant cell culture work, including the isolation, growth and maintenance of primary cells, such as endothelial cells from various organs, and characterizing these cells using techniques such as flow cytometry and ELISA. To be successful in this role, you will leverage previous experience with immunological and genomic assays. This role is a full-time lab-based position in which being proactive, determined, responsible, coachable, and collaborative will help you thrive.

PRIMARY RESPONSIBILITIES


  • Develop, optimize, and execute robust and reproducible assays
  • Utilize various techniques to characterize the primary cells and/or factors they produce, including flow cytometry, ELISA, conventional and real-time PCR, etc.
  • Isolate, culture, and assess the function of porcine cells
  • Communicate and present scientific findings at group and company meetings
  • Implement superb documentation of procedures and experiments to support tech transfer
  • Contribute to multiple research projects as they arise in our fast-paced, start-up environment
  • Troubleshoot and optimize assays and maintain careful records
  • Build our laboratory efforts by maintaining and creating a productive and fun environment

BASIC QUALIFICATIONS


  • Ph.D. with 2 years of industry experience, or MS degree with 4+ years of industry experience in cell biology, immunology, biochemistry or related discipline
  • Prior experience in development and execution of assays to characterize and measure proteins and DNA using a variety of methodologies, particularly flow cytometry
  • Proficiency in growing and maintaining mammalian cells in culture and aseptic cell culture techniques
  • Expertise in general cellular and molecular biology techniques, including ELISA, FACS, flow cytometry, RNA/DNA isolation etc.
  • Demonstrated experience leading a team and developing talent
  • Strong communication and organizational skills, and ability to prioritize and multitask efficiently in a results-oriented, dynamic environment
  • Strong interpersonal skills and ability to work in teams

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This job is no longer open

Life at eGenesis

eGenesis is revolutionizing the field of transplantation with an unparalleled, multiplexed gene editing platform for the development of human-compatible organs, tissues and cells. Harnessing the latest gene-editing techniques, eGenesis has the capability to solve the global organ crisis by providing an alternative to allotransplantation. eGenesis is uniquely positioned to reinvigorate the field of xenotransplantation by addressing both the key virology and immunology hurdles that have impeded its advancement to date and provide commercially-viable products to save and enhance the lives of patients in need.
Thrive Here & What We Value- Promoting safety in the workplace- Maintaining high standards of animal care and welfare- Collaborating with Farm Operations Team members- Providing animal care areas according to SOPs- Following Vet Staff instructions for treatments- Delivering safe human transplantable cells, tissue, organs using genome editing- Maintaining high quality standards in donor production- Collaborative work environment- Emphasis on animal welfare and biosecurity practices- Supportive leadership and career development opportunities
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