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Director, Analytical Development

ArcellxRockville, Maryland, United StatesOnsite
This job is no longer open

Who We Are


Arcellx isa public, clinical-stage biotechnology company reimagining cell therapy by engineering innovative immunotherapies for patients with cancer and other incurable diseases. We believe that cell therapies are one of the forward pillars of medicine and our mission is to destroy cancer and advance humanity by developing cell therapies that are safer, more effective, and more broadly accessible.Our team members are made up of talented innovators and dreamers working from our offices in Rockville, Maryland, and Redwood City, California.

At Arcellx, we hire exceptional people and create a fun, diverse, supportive, and informal environment that allows everyone to do their best work.

What Matters to Us


Living our core values is essential to maintaining a work environment that is high-performing, inclusive, and collaborative. We look for candidates who demonstrate strong values alignment and bring different backgrounds, viewpoints, and abilities to the team.Arcellx Core Values

  • Character: Committed to always doing what’s right.
  • Audacity: Willing to challenge convention and share candid feedback with others.
  • Determination: Curious and self-motivated. Always looking to improve and learn.  
  • Collaboration: "No job is too small" mentality. Humble and willing to help others.
  • Originality: Will bring your unique perspective to the table and respect a diverse set of views and backgrounds.

The “Fine Print” – What You’ll Do


  • Design and execute method development and qualification in support of process development, product release and stability, product characterization, investigation, and process performance qualification.
  • Direct phase-appropriate assay development, qualification, and transfer for starting material, raw material, drug substance and drug product.
  • Oversee analytical technical activities at a CDMO in support of product development on accelerated timelines, including late-stage product characterization, risk assessments, and establishment of QTPP and control of CQAs.
  • Prepare and review documents in support of CMC Regulatory IND filings and address queries from health authorities.
  • Guide the analytical team to support career growth and development in experiment design, data analysis, documentation, and communication/reporting.

Skills and Experience We Look For


  • PhD. or master’s degree in immunology and cellular biology or a related discipline.
  • 8+ years (with PhD) or 12+ years (with MS) of experience in late-stage analytical development for cell therapeutics.
  • Excellent organizational skills and an ability to prioritize effectively to deliver results within aggressive timelines.
  • Detail-oriented individual with strong analytical and problem-solving skills.
  • Strong collaboration, communication, and interpersonal skills. Demonstrated ability to influence within a matrix team structure.

Rewards at Arcellx


Our people are our greatest asset, and supporting their well-being is an essential part of delivering on our mission and impacting the lives of patients. Putting this belief into practice means offering strong compensation and benefits.In addition to a competitive base salary, our compensation package includes an annual bonus based on company goals and an equity (RSU) grant. We do offer relocation assistance for roles if required.Our market-leading benefits package includes: 100% coverage for medical, dental and vision for team members and dependents, unlimited vacation, a 3-day weekend every month, fully-paid parental leave for up to 6 months, tuition reimbursement, 401k employer contribution and more. 

Join us in our quest to reimagine cell therapy and destroy cancer. For more on our technology, culture, and team, go to


www.arcellx.com


.


 #LI-Onsite

This job is no longer open

Life at Arcellx

Arcellx is a clinical-stage biopharmaceutical company developing novel, adaptive and controllable cell therapies for the treatment of patients with cancer and autoimmune diseases. The Company's proprietary ARC-sparX platform separates the tumor-recognition and tumor-killing functions of conventional CAR-T cell therapies: (1) sparX (soluble protein antigen-receptor X-linkers) proteins recognize and bind specific antigens on diseased cells and flag those cells for destruction; and (2) ARC-T (Antigen Receptor Complex-T) cells bind the sparX proteins and kill the flagged cells. Arcellx has developed a collection of sparX proteins that bind different cell surface antigens. Administration of alternate sparX proteins can redirect ARC-T cells to different disease antigens to potentially address relapsed and refractory disease due to tumor heterogeneity or antigen escape. Additionally, ARC-T cell activity can be curbed as needed by controlling the dose and frequency of sparX administration.
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