logo inner

Senior Scientist, Translational Sciences

ArcellxRockville, Maryland, United StatesOnsite
This job is no longer open

Who We Are


Arcellx isa public, clinical-stage biotechnology company reimagining cell therapy by engineering innovative immunotherapies for patients with cancer and other incurable diseases. We believe that cell therapies are one of the forward pillars of medicine and our mission is to destroy cancer and advance humanity by developing cell therapies that are safer, more effective, and more broadly accessible.Our team members are made up of talented innovators and dreamers working from our offices in Rockville, Maryland, and Redwood City, California.

At Arcellx, we hire exceptional people and create a fun, diverse, supportive, and informal environment that allows everyone to do their best work.

What Matters to Us


Living our core values is essential to maintaining a work environment that is high-performing, inclusive, and collaborative. We look for candidates who demonstrate strong values alignment and bring different backgrounds, viewpoints, and abilities to the team.Arcellx Core Values

  • Character: Committed to always doing what’s right.
  • Audacity: Willing to challenge convention and share candid feedback with others.
  • Determination: Curious and self-motivated. Always looking to improve and learn.  
  • Collaboration: "No job is too small" mentality. Humble and willing to help others.
  • Originality: Will bring your unique perspective to the table and respect a diverse set of views and backgrounds.

The “Fine Print” – What You’ll Do


  • Contribute relevant scientific expertise, strategy, and experimentally derived insights as a member of multidisciplinary project teams working to drive the preclinical to clinical translation of pipeline assets.
  • Plan, design, and execute IND-enabling pharmacology, pharmacokinetic and toxicology studies by applying knowledge of disease-associated pathways, preclinical models, and drug development.
  • Contribute to the preparation of IND applications and other regulatory documents.
  • Collaborate cross-functionally to enable translation of preclinical hypotheses into clinical biomarker strategies and to guide patient stratification.
  • Design and conduct studies to inform disease area strategy for target selection and validation.
  • Establish and cultivate relationships with external CRO collaborators for basic and translational research.
  • Analyze and interpret experimental data readouts and present results at internal meetings and scientific conferences.
  • Maintain an awareness of new/emerging techniques, tools and clinical findings relevant to the field.

Skills and Experience We Look For


  • PhD, MD or MD/PhD degree in a relevant scientific field (g., cancer biology, immunology, molecular biology, bioinformatics) with 0-2 years’ experience in drug discovery or drug development.
  • Demonstrated record of research accomplishment as evidenced by publications or major contributions to drug development milestones.
  • Experience with large, multimodal data sets and familiarity with techniques for exploring associations of biomarkers with clinical outcomes.
  • Strategic thinker with proven leadership skills and/or prior project team leadership roles.
  • Proficiency in distilling complex issues and clearly articulating viable paths forward.

Rewards at Arcellx


Our people are our greatest asset, and supporting their well-being is an essential part of delivering on our mission and impacting the lives of patients. Putting this belief into practice means offering strong compensation and benefits.In addition to a competitive base salary, our compensation package includes an annual bonus based on company goals and an equity (RSU) grant. We do offer relocation assistance for roles if required.Our market-leading benefits package includes: 100% coverage for medical, dental and vision for team members and dependents, unlimited vacation, a 3-day weekend every month, fully-paid parental leave for up to 6 months, tuition reimbursement, 401k employer contribution and more. 

Join us in our quest to reimagine cell therapy and destroy cancer. For more on our technology, culture, and team, go to


www.arcellx.com


.


 #LI-Onsite

This job is no longer open

Life at Arcellx

Arcellx is a clinical-stage biopharmaceutical company developing novel, adaptive and controllable cell therapies for the treatment of patients with cancer and autoimmune diseases. The Company's proprietary ARC-sparX platform separates the tumor-recognition and tumor-killing functions of conventional CAR-T cell therapies: (1) sparX (soluble protein antigen-receptor X-linkers) proteins recognize and bind specific antigens on diseased cells and flag those cells for destruction; and (2) ARC-T (Antigen Receptor Complex-T) cells bind the sparX proteins and kill the flagged cells. Arcellx has developed a collection of sparX proteins that bind different cell surface antigens. Administration of alternate sparX proteins can redirect ARC-T cells to different disease antigens to potentially address relapsed and refractory disease due to tumor heterogeneity or antigen escape. Additionally, ARC-T cell activity can be curbed as needed by controlling the dose and frequency of sparX administration.
Your tracker settings

We use cookies and similar methods to recognize visitors and remember their preferences. We also use them to measure ad campaign effectiveness, target ads and analyze site traffic. To learn more about these methods, including how to disable them, view our Cookie Policy or Privacy Policy.

By tapping `Accept`, you consent to the use of these methods by us and third parties. You can always change your tracker preferences by visiting our Cookie Policy.

logo innerThatStartupJob
Discover the best startup and their job positions, all in one place.
Copyright © 2024