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Director, Program Lead

ArcellxOnsite
This job is no longer open

Who We Are


Arcellx isa public, clinical-stage biotechnology company reimagining cell therapy by engineering innovative immunotherapies for patients with cancer and other incurable diseases. We believe that cell therapies are one of the forward pillars of medicine and our mission is to destroy cancer and advance humanity by developing cell therapies that are safer, more effective, and more broadly accessible.Our team members are made up of talented innovators and dreamers working from our offices in Rockville, Maryland, and Redwood City, California.

At Arcellx, we hire exceptional people and create a fun, diverse, supportive, and informal environment that allows everyone to do their best work.

What Matters to Us


Living our core values is essential to maintaining a work environment that is high-performing, inclusive, and collaborative. We look for candidates who demonstrate strong values alignment and bring different backgrounds, viewpoints, and abilities to the team.Arcellx Core Values

  • Character: Committed to always doing what’s right.
  • Audacity: Willing to challenge convention and share candid feedback with others.
  • Determination: Curious and self-motivated. Always looking to improve and learn.  
  • Collaboration: "No job is too small" mentality. Humble and willing to help others.
  • Originality: Will bring your unique perspective to the table and respect a diverse set of views and backgrounds.

How You’ll Make a Difference


As our Director, Pipeline Strategy, you’ll use your expertise in crafting and delivering drug development strategies to manage pipeline projects from clinical candidate nomination through clinical proof of concept, including assessing ongoing project viability, management and oversight of key preclinical data updates, and readiness for IND preparation and filings.This role has broad impact across the organization, working with cross-functional stakeholders, including senior management, to ensure alignment, timely decision making, and escalation of project challenges, ultimately maximizing the likelihood of clinical and commercial success.

The “Fine Print” – What You’ll Do


  • Accountable for developing and driving project strategy with scientific rigor in alignment with portfolio strategy.
  • Manage the project timeline and budget across cross-functional workstreams, ensuring alignment of key deliverables, anticipating and mitigating risks, and driving accountability across the organization.
  • Partner with functional leads to support CMC development and commercialization activities and ensure adequate clinical supply for the early and late-stage portfolio.
  • Identify, develop, articulate, and present strategic options to make the best trade-off decisions within a project (e.g., technical product profile alterations, clinical product considerations) and across the portfolio as needed given changing market conditions or key early-stage data outputs.
  • Present critical program updates for data read-outs or notable preclinical / clinical milestones to senior leadership.
  • Ensure appropriate visibility to the organization on timeline, progress-to-date, upcoming key milestones, and identified risks.
  • Escalate and resolve key issues with the senior management team.

Skills and Experience We Look For  


  • PhD or MD with 8+ years of industry experience.
  • Expertise in developing immunotherapies for cancer.
  • Broad understanding of the evolving clinical and global commercial landscape in oncology, autoimmune and inflammatory diseases, and cell therapy.
  • Outstanding strategic planning and analytical skills with the ability to synthesize findings and articulate implications from multiple sources of information to formulate strong recommendations and uncover market opportunities.
  • Mastery of project management tools and timeline management.
  • Demonstrated experience leading at scale, motivating teams, and influencing senior leaders and key stakeholders.
  • Ability to take initiative, build productive relationships, work cross-functionally, and manage multiple projects.

Rewards at Arcellx


Our people are our greatest asset, and supporting their well-being is an essential part of delivering on our mission and impacting the lives of patients. Putting this belief into practice means offering strong compensation and benefits.The base salary range for this position is $230,000 - $255,000 per year. Where a candidate falls within that range is determined by factors such as years of experience. Our compensation package also includes an annual bonus based on company goals and an equity (RSU) grant.

We do offer relocation assistance for roles if required.Our market-leading benefits package includes: 100% coverage for medical, dental and vision for team members and dependents, unlimited vacation, a 3-day weekend every month, fully-paid parental leave for up to 6 months, tuition reimbursement, 401k employer contribution and more. 

Join us in our quest to reimagine cell therapy and destroy cancer. For more on our technology, culture, and team, go to


www.arcellx.com


.


 #LI-Onsite

This job is no longer open

Life at Arcellx

Arcellx is a clinical-stage biopharmaceutical company developing novel, adaptive and controllable cell therapies for the treatment of patients with cancer and autoimmune diseases. The Company's proprietary ARC-sparX platform separates the tumor-recognition and tumor-killing functions of conventional CAR-T cell therapies: (1) sparX (soluble protein antigen-receptor X-linkers) proteins recognize and bind specific antigens on diseased cells and flag those cells for destruction; and (2) ARC-T (Antigen Receptor Complex-T) cells bind the sparX proteins and kill the flagged cells. Arcellx has developed a collection of sparX proteins that bind different cell surface antigens. Administration of alternate sparX proteins can redirect ARC-T cells to different disease antigens to potentially address relapsed and refractory disease due to tumor heterogeneity or antigen escape. Additionally, ARC-T cell activity can be curbed as needed by controlling the dose and frequency of sparX administration.
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