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Associate Scientist

ArcellxRockville, Maryland, United StatesOnsite
This job is no longer open

Who We Are


Arcellx is a public, clinical-stage biotechnology company reimagining cell therapy by engineering innovative immunotherapies for patients with cancer and other incurable diseases. We believe that cell therapies are one of the forward pillars of medicine and our mission is to destroy cancer and advance humanity by developing cell therapies that are safer, more effective, and more broadly accessible.Our team members are made up of talented innovators and dreamers working from our offices in Gaithersburg, Maryland, and Redwood City, California.

At Arcellx, we hire exceptional people and create a fun, diverse, supportive, and informal environment that allows everyone to do their best work.

What Matters to Us


Living our core values is essential to maintaining a work environment that is high-performing, inclusive, and collaborative. We look for candidates who demonstrate strong values alignment and bring different backgrounds, viewpoints, and abilities to the team.Arcellx Core Values

  • Character: Committed to always doing what’s right.
  • Audacity: Willing to challenge convention and share candid feedback with others.
  • Determination: Curious and self-motivated. Always looking to improve and learn.  
  • Collaboration: "No job is too small" mentality. Humble and willing to help others.
  • Originality: Will bring your unique perspective to the table and respect a diverse set of views and backgrounds.

How You’ll Make a Difference


As an Associate Scientist, you will use molecular biology, protein purification and characterization methods to support Discovery's protein engineering and technology development efforts. Engaging with a cross-functional team in a fast-paced environment, you’ll identify and develop Arcellx’s lead therapeutic candidates. Our potentially life-saving treatments would not exist without the work of our talented Discovery scientists; this role will have a tremendous impact on our pipeline and ability to deliver novel and effective drugs to patients.

  

The “Fine Print” – What You’ll Do


  • Work with other scientists to design, generate and characterize recombinant proteins to be used in cancer therapy discovery and development.
  • Assist with selection and/or screening strategies used in protein discovery workflows employing phage display, yeast display, ELISA, BLI and flow cytometry as needed.
  • Communicate detailed observations on experiments and assist in the preparation of technical reports, summaries, and protocols.

Skills and Experience We Look For


  • Bachelor’s or master’s degree in the life sciences (e.g., biology, genetics, biochemistry, chemistry, chemical engineering, bioengineering).
  • Minimum of 3 years of experience in a laboratory setting.
  • Ability to work both independently and collaboratively. Ability to effectively plan, organize, and prioritize work activities.
  • Must demonstrate proficiency with molecular biology methods, including primer design, PCR, gel electrophoresis, plasmid DNA preparation, cloning and sequence analysis using SnapGene or similar software.
  • Preferred skills include those related to recombinant protein expression (e.g. transient transfection), purification (e.g. nickel and Protein A affinity chromatography) and characterization (e.g. ELISA, BLI, SDS-PAGE, protein quantitation and flow cytometry).

Rewards at Arcellx


Our people are our greatest asset, and supporting their well-being is an essential part of delivering on our mission and impacting the lives of patients. Putting this belief into practice means offering strong compensation and benefits.In addition to a competitive base salary, our compensation package includes an annual bonus based on company goals and an equity (RSU) grant. We do offer relocation assistance for roles if required.Our market-leading benefits package includes: 100% coverage for medical, dental and vision for team members and dependents, unlimited vacation, a 3-day weekend every month, fully-paid parental leave for up to 6 months, tuition reimbursement, 401k employer contribution and more. 

Join us in our quest to reimagine cell therapy and destroy cancer. For more on our technology, culture, and team, go to


www.arcellx.com


.


 #LI-Onsite

This job is no longer open

Life at Arcellx

Arcellx is a clinical-stage biopharmaceutical company developing novel, adaptive and controllable cell therapies for the treatment of patients with cancer and autoimmune diseases. The Company's proprietary ARC-sparX platform separates the tumor-recognition and tumor-killing functions of conventional CAR-T cell therapies: (1) sparX (soluble protein antigen-receptor X-linkers) proteins recognize and bind specific antigens on diseased cells and flag those cells for destruction; and (2) ARC-T (Antigen Receptor Complex-T) cells bind the sparX proteins and kill the flagged cells. Arcellx has developed a collection of sparX proteins that bind different cell surface antigens. Administration of alternate sparX proteins can redirect ARC-T cells to different disease antigens to potentially address relapsed and refractory disease due to tumor heterogeneity or antigen escape. Additionally, ARC-T cell activity can be curbed as needed by controlling the dose and frequency of sparX administration.
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