Adaptimmune is a fully integrated cell therapy company, designed and built from the ground up with four U.K.- and U.S.-based biotechnology hub locations. Our comprehensive capabilities and teams include preclinical research, clinical development, translational sciences, autologous and allogeneic manufacturing, and in-house commercial and corporate operations.Our company culture is rooted in trust, inclusion, our capacity to collaborate, and our commitment to being honest and brave in our desire to successfully transform the lives of people with cancer.
Primary ResponsibilityThe Vector Process & Analytical Development team is focused on the development of Adaptimmune’s Lentiviral Vectormanufacturing process, and the development and qualification of the analytical assays used for Lentiviral Vector characterisation and release. The purpose of this role is to support these functions.A Scientist is required to join the team to contribute to the Vector PD&AD team function by performing following duties:
- Planning and execution of experimental work
- Interpretation of results (collaborating with a Senior Scientist)
- Accurate recording of experimental data
- Maintenance of cell cultures
- Production and purification of viral vectors
- Maintenance of laboratory equipment
The Scientist may also be involved in one or more support activities to enable the smooth running of the group or laboratory (e.g. Lab Steward role).Performance in this role (including functional and project objectives and behaviours) is expected to be monitored through group performance and stakeholder feedback from peers, senior management and project team members (as outlined in the development framework for this position).Key Responsibilities
- Conducting lab work to progress the group and company objectives.
- In collaboration with other team members, logistically plan, analyse, summarise and record experimental results, and maintain relevant databases and records.
- Participating in group and project meetings and discussions
- Routine lab maintenance
Qualifications & Experience
Minimum Required
- Undergraduate degree in Life Sciences, or related discipline
- At least 3 years of relevant laboratory experience
- Experience of either: running or developing assays used to characterise Viral Vectors or experience in running or developing vector production/purification methods.
- Practical experience with some of the following: mammalian cell culture, cell-based assays, ELISA, nucleic acid extraction, qPCR, flow cytometry, upstream bioprocessing, downstream bioprocessing.
Desirable
- Experience working in a commercial / industrial laboratory environment.
- Awareness of regulatory guidelines and expectations around assay or process validation.
At Adaptimmune we embrace diversity and equality of opportunity. We believe that the more inclusive we are, the better our work will be. We welcome applications to join our team from all qualified candidates, regardless of age, colour, disability, marital status, national origin, race, religion, gender, sexual orientation, gender identity, veteran status or other legally protected category. It is our intent that all qualified applicants will receive equal consideration for employment.
