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Immunology Research Associate I, II

GenEditBrisbane, Australia | California, United StatesOnsite
This job is no longer open

Immunology Research Associate I, II


GenEdit is a rapidly-growing, early-stage company that is developing a proprietary and novel delivery platform with the potential to transform genetic medicine. Our interdisciplinary team works together across chemistry, payload design, formulation, and screening and preclinical groups to develop the next generation of gene therapies. GenEdit fosters an exciting and dynamic environment where we value impactful data and creative solutions to accelerate our progression from a platform technology to a pipeline of therapeutic candidates.

We are seeking talented and motivated individuals to join our team and are expanding across all functions within the organization. Join us in South San Francisco, CA, to be at the forefront of the future of gene therapy.

Job Description


We are seeking a talented and motivated research associate to join our team and help drive the development of genetic medicines for immune-based diseases utilizing our hydrophilic nanoparticle (HNP) technology. This individual will be part of the Immune Program Team and will be responsible for executing studies as directed by the supervisor. She/he will be a key contributor to in vitro and ex vivo assay method development, HNP and payload screening, and ex vivo assays of tissue samples to identify lead therapeutic candidates that achieve desired immune modulating activity.

The ideal individual will have a strong background in cellular immunology, immune response regulation, and immunological assays. Individuals with industry experience as a key individual contributor on project teams and a successful track record of teamwork are preferred. Position title will be commensurate with scope of responsibilities and years of relevant experience.

Education and Qualifications


·Bachelor or Master’s degree in Immunology, Cell Biology, or related field·Minimum of 2 years full-time research in industry or 3 years academic lab experience with a focus on immune assays·Work authorization in the US is required

Required Skills


·Cell culture of primary immune cells (PBMC, APC, DC, T cells) and immune cell linesIn vitro immune-based assays including but not limited to multicolor flow cytometry and analysis (FlowJo), cytokine analysis (MSD, Luminex), ELISA, ELISpotIn vitro immune cell-based assays including but not limited to T cell:DC co-culture, cytotoxic T cell killing assay, MLRIn Vitro screening, microplate cell-based assays, protein expression, viability, cytotoxicity, fluorescence, luminescence, automated microscopy and image analysisExperience with spleen, bone marrow and other immune tissue harvest and processing for ex vivo assaysExperience with molecular biology is a plus (nucleic acid and protein extraction and purification, electrophoresis, PCR, RT-qPCR)Ability to execute on research protocols with accuracy and precisionExcellent communication and organizational skills, ELN record keepingAt GenEdit we are always looking to hire the absolute best talent and recognize that diversity in our experiences and backgrounds is what makes us stronger.

We hire candidates of any race, color, ancestry, religion, sex, national origin, sexual orientation, gender identity, age, marital or family status, disability, veteran status, and any other status. These differences are what enable us to work towards the future we envision for ourselves, and the world.Apply for this job

This job is no longer open

Life at GenEdit

GenEdit is a next-generation genome editing company. We are developing non-viral delivery technologies for the CRISPR/Cas9 gene editing system that can safely and efficiently correct gene mutations in patients. CRISPR/Cas9 is a powerful genome editing tool that makes therapeutic gene editing possible. It is easier to use, faster, and more accurate than previous gene editing techniques and thus has the potential for a wide range of therapeutic applications. In particular, CRISPR/Cas9 gene editing has the potential to treat a variety of incurable genetic diseases. However, current CRISPR delivery methods rely on viruses and are problematic due to viral-induced toxicity and prolonged Cas9 exposure, increasing off-target effects. A non-viral CRISPR/Cas9 delivery method is needed. In addition, low efficiency levels achieved make it impossible to target certain diseases. GenEdit's novel CRISPR delivery technology has the potential to be a platform delivery system for a broad range of genetic diseases. We also work on engineering of core components of CRISPR/Cas9 genome editing system to increase editing efficiency and enable targeted delivery.
Thrive Here & What We Value1. Dynamic and exciting environment2. Valuing impactful data and creative solutions3. Emphasis on teamwork and collaboration4. Commitment to advancing novel therapies in genetic medicine5. Diversity as a strength6. Inclusive hiring practices
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