Xilis, Inc. is an innovation-driven biotech company developing its proprietary MicroOrganoSphere (“MOS”) Technology for functional precision oncology. Xilis’ MOS Technology enables rapid and scalable generation of patient tumor models that retain patient-specific tumor biology and tumor microenvironment, representing one of the most translationally-relevant ex vivo technologies for precision oncology drug discovery and development. Located in Research Triangle Park, Durham, NC, Xilis is building a functional precision medicine platform that incorporates scaled multi-modal profiling of therapeutic activity and AI/ML-enabled analytics to catalyze functional precision medicine drug discovery, development and diagnostics. Collectively, Xilis aims to harness its MOS Platform to enable development of the most effective therapeutics and guide them to the right patients at the right time.
Role
The candidate will be responsible for the management of reagent production and documentation in accordance with SOPs and CLIA regulatory guidelines, and to improve and streamline those processes. This will include assisting with the development of Standard Operating Procedures (SOP); establishing and performing equipment validation and maintenance procedures; maintaining critical reagent inventory tracking and QC; and assisting with establishing laboratory training procedures. The successful candidate will bring exceptional skills and abilities to the laboratory. He or she will also have strong attention to detail and the integrity to precisely report any deviation or issue observed in the laboratory.
Finally, the candidate’s communication skills will be stellar. The candidate will report to Xilis’ Manager of Laboratory Operations. By joining the team at an early stage, the candidate will have an outsized impact on fundamentally advancing precision cancer care therapy.
Responsibilities
- Participate in all phases of clinical and biological production under cGMP conditions
- Assist with maintaining laboratory inventory and procurement of reagents and materials
- Perform routine equipment maintenance and cleaning
- Assist with the improvement of Standard Operating Procedures (SOPs)
- Work closely with the assay development, operations and quality teams to develop and maintain quality assurance (QA) and quality control (QC) protocols
- Identify and document potential QC or processing issues and report to management
- Operate successfully in a rapidly changing, fast paced, mission-driven environment
- Share thoughts and ideas on how to improve performance in the lab
- Perform support tasks across the company as needs arise
Requirements
- A B.S. or M.S. degree in biology, biological sciences, molecular biology, biomedical engineering, or equivalent
- 2+ years of experience in a laboratory environment
- Hands-on laboratory experience, including reagent production and clinical sample processing
- Experience with cell and tissue culture is a plus
- A strong sense of commitment, integrity and handling challenges collaboratively
- Experience and interest in a high-growth startup, where communication is key
* Some work will be required on evenings and weekends.
Xilis was created when its three founders — an engineer, a physician, and a biologist — decided to come together and commercialize their technology to transform cancer care. We are committed to building a team that represents a variety of backgrounds, perspectives, and skills. We do not discriminate on the basis of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, or Veteran status. Furthermore, even if your work experience isn't perfectly aligned with what we've described above, if you're excited about what we're building then we want to talk to you!Xilis offers comprehensive health, vision, dental & retirement plans, and unlimited PTO.
We are a remote-friendly team: our headquarters are in Durham, North Carolina, but we have team members across the US (and beyond!). Apply for this job
