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Research Associate I

CytokineticsSouth San Francisco, California, United StatesOnsite
This job is no longer open

Cytokinetics is a late-stage, specialty cardiovascular biopharmaceutical company focused on discovering, developing and commercializing first-in-class muscle activators and next-in-class muscle inhibitors as potential treatments for debilitating diseases in which cardiac muscle performance is compromised. As a leader in muscle biology and the mechanics of muscle performance, the company is developing small molecule drug candidates specifically engineered to impact myocardial muscle function and contractility.
We are currently in search of a highly motivated Research Associate who possesses a strong passion for the field of Medicinal Chemistry, to become an integral part of our dynamic team. The ideal candidate will bring forth their expertise and enthusiasm to actively contribute to and enhance our ongoing efforts and initiatives in the realm of pharmaceutical research and development.

Responsibilities


  • Under supervision design and synthesize next generation compounds by application of medicinal chemistry knowledge to the analysis of potency, DMPK, and off-target selectivity data.
  • Accomplish the synthesis of enough designed target molecules and key intermediates with high productivity for biological, DMPK and in vivo studies.
  • Summarize/interpret data and present findings in research meetings.
  • Maintain detailed experimental records; Documents of experiments in the electronic lab notebook should be in full compliance with the guidelines established within the company and chemistry department.
  • Use software infrastructure including Scifinder, ChemCart,,Spotfire, Stardrop and Moe to carry out daily research activities efficiently.
  • Help maintain research lab productivity by adhering to outlined group responsibilities and safety procedures. Manage the medicinal chemistry group inventory; track and order the supply weekly
  • Attend and present posters at scientific /technical conferences; Contribute to scientific paper and /or patents.

Qualifications


  • B.S. in scientific discipline with 0-2 years of related experience and understanding of medicinal chemistry.
  • Has experience maintaining lab equipment along with inventory levels of supplies.
  • Proven analytical and problem-solving skills, with the ability to critically evaluate and interpret experimental data.
  • Understands and acts on detailed instructions while also demonstrating initiative.

Actual salary at the time of hire may vary and may be above or below the range based on various factors, including, but not limited to, the candidate’s relevant qualifications, skills, and experience, as well as the service line and location where this position may be filled.Salary Pay Range$75,000—$91,000 USDOur employees come from different backgrounds, and we celebrate those differences. We are looking for the best candidates for our open roles, but do not expect applicants to meet every qualification in order to be considered.

If you are excited about what you could accomplish at Cytokinetics and believe you can add value to our team, we would love to hear from you.

Please review our General Data Protection Regulation (GDPR) policy PRIOR to applying.  


Our passion is anchored in robust scientific thinking, grounded in integrity and critical thinking. We keep the patient front and center in all we do – all actions and decisions are in service of the patient and their caregivers. We champion integrity, ethics, doing the right thing, and being our best selves.

Please visit our website at: www.cytokinetics.com


Cytokinetics is an Equal Opportunity Employer



This job is no longer open

Life at Cytokinetics

We are a leading biopharmaceutical company focused on the discovery, development and commercialization of novel small molecule drugs that specifically target the cytoskeleton. The cytoskeleton is a complex biological infrastructure that plays a fundamental role within every human cell. A number of commonly used drugs and a growing body of research validate the role that the cytoskeleton plays in a wide array of human diseases. Our focus on the cytoskeleton enables us to develop novel and potentially safer and more effective classes of drugs directed at treatments for cancer, cardiovascular disease, fungal diseases and other diseases. We have developed a cell biology driven approach and proprietary technologies to evaluate the function of many interacting proteins in the complex environment of the intact human cell. We believe that our approach enhances the speed, efficiency and yield of our drug discovery and development process by accurately and rapidly identifying drug candidates with attractive properties. Our approach has yielded two drug candidates for the treatment of cancer, a drug candidate for the treatment of acute congestive heart failure and more than ten other research programs. Our most advanced drug candidate, SB-715992, is the subject of a broad Phase II clinical trials program designed to evaluate its effectiveness in many different types of cancer. An investigational new drug application, or IND, was filed with the U.S. Food and Drug Administration, or FDA, in 2003 for our second cancer drug candidate, SB-743921, which we expect will enter Phase I clinical development in early 2004. SB-715992 and SB-743921 are being developed through our strategic alliance with GlaxoSmithKline. In addition, we expect to initiate Phase I clinical development for a drug candidate, CK-1213296, for the treatment of acute congestive heart failure in the second half of 2004.
Thrive Here & What We Value1. Passionate about robust scientific thinking grounded in integrity and critical thinking2. Celebrates differences among employees3. Patient-centric approach to all actions and decisions4. Values integrity, ethics, doing the right thing, and being our best selves5. Emphasis on patient-centered care6. Focus on innovation and continuous improvement7. Dedicated to keeping the patient front and center in all actions and decisions8. Values-driven and sustainable approach to drug discovery and development9. Rigorous scientific thinking and critical thinking10. Emphasis on collaboration across different departments and teams
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