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Manager, Engineering

AtomwiseSan Francisco, California, United States | San Diego, California, United StatesRemote, Onsite
This job is no longer open

Atomwise is a TechBio company leveraging AI/ML to revolutionize small molecule drug discovery. The Atomwise team invented the use of deep learning for structure-based drug design; a core technology of Atomwise’s best-in-class AI discovery and optimization engine, which is differentiated by its ability to find and optimize novel chemical matter. The company’s belief is that structurally novel chemical matter increases the likelihood of developing first-in-class and best-in-class medicines that have the potential to transform patient care.
Atomwise has extensively tested its discovery and optimization engine, delivering hit ID success in over 230 academic and collaboration projects-to-date that cover a wide breadth of protein classes and numerous “hard-to-drug” targets. Atomwise is building a wholly-owned pipeline of small molecule drug candidates and plans to file an IND application this year for its lead candidate, a novel allosteric TYK2 inhibitor with first-in-class and best-in-class potential.The company has raised over $174 million from leading venture capital firms to advance its vision to invent a better way to discover and develop new medicines to help patients.

About the role


Our Technology Team is a small, cohesive, remote team that owns the drug discovery platform. As the Manager of Software Engineering, you will manage a team that owns everything from data management tools to advanced science-based machine learning algorithms to help our scientists perform significant advances in drug discovery. This role reports to the CTO.

Key Responsibilities


  • Collaborate with executive leadership across machine learning, cheminformatics, and drug discovery to anticipate business requirements and invent technical solutions.
  • Define and drive the overall technical vision for software development.
  • Tech-first leader, someone who wants to dive into the technology and be a partner to senior engineers on the team.
  • Directly manage a team of engineers, overseeing project timelines, deliverables, and team performance.
  • Drive the implementation of high-impact, innovative solutions.
  • Contribute to the codebase by writing well-architected and maintainable Python code.
  • Lead the evaluation and adoption of new technologies.
  • Foster a collaborative and inclusive team culture, ensuring the professional growth and well-being of team members.

Required Qualifications


  • 5+ years of hands-on software development experience.
  • Extensive experience in one object-oriented programming language (Python, Java, C++, etc).
  • Expertise in cloud platforms and containerization (AWS, Kubernetes).
  • Proven experience in defining technical strategies and architectures.
  • Strong leadership and strategic thinking skills.
  • 3+ years of management experience.

Preferred Qualifications


  • Track record of working on technology within TechBio/BioTech vertical.
  • Extensive expertise in SQL and relational databases.
  • Experience with workflow systems - e.g. Flyte, Argo, MLFlow.

Compensation & benefits


  • Competitive salary, commensurate with experience.
  • Stock compensation plan – you’ll be an Atomwise co-owner.
  • Platinum health, dental, and vision benefits for you and your dependents.
  • 401(k) retirement plan with generous company match (up to 4%).
  • Flexible paid time off (PTO), 13 paid holidays, and wellness breaks for employees to spend time with their loved ones and recharge.
  • Health Savings and Flexible Spending Account options to help save money on healthcare, daycare, and commuting.
  • Employee Assistance Program (EAP) and Pet Insurance.
  • Funding for professional development and conference attendance.
  • Flexible work schedule.
  • Generous paid parental leave.

Atomwise is an equal opportunity employer and strives to foster an inclusive workplace.  Our mission is to develop better medicines faster, and we know that we need a diverse team to develop medicines that serve diverse populations.  Accordingly, Atomwise does not make any employment decisions (including but not limited to, hiring, compensation, and promotions) on the basis of race, religion, color, national origin, gender, gender identity, sexual orientation, age, veteran status, disability status, or any other characteristics protected by applicable federal, state, and local law.We strongly encourage people of diverse backgrounds and perspectives to apply.*Pay range for this role is between $140,000 - $190,000*

This job is no longer open

Life at Atomwise

Atomwise uses Deep Learning Neural Networks to help discover new medicines. Atomwise achieves the world's best results for new drug hit discovery, binding affinity prediction, and toxicity detection. Atomwise predicts drug candidates for pharmaceutical companies, startups, and research institutions.
Thrive Here & What We Value- Competitive salary, commensurate with experience- Stock compensation plan – coowner of Atomwise- Platinum health, dental, vision benefits for dependents- 401(k) retirement plan with generous company match (up to 4%)- Flexible paid time off, 13 paid holidays, wellness breaks- Health Savings and Flexible Spending Account options- Employee Assistance Program (EAP), Pet Insurance- Funding for professional development and conference attendance- Flexible work schedule- Generous paid parental leave
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