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Scientist II

InflammatixLisbon, PortugalOnsite
This job is no longer open

Inflammatix Portugal is seeking a highly motivated
Scientist Level II to contribute to assay development activities supporting microfluidic test system development. The successful candidate will play a key role in advancing our research and development projects, particularly in the areas of ultra-rapid sample preparation, isothermal amplification protocols, and microfluidic device development. This role is laboratory-based and requires exceptional attention to detail. This role will involve development of novel sample preparation methods and Design of Experiments-based (DOE-based) optimization of existing chemistries.

The successful candidate will work collaboratively within a multidisciplinary team to achieve project goals and drive innovation.PRIMARY RESPONSIBILITIES:

  • Design, develop, and optimize molec ular assays, including but not limited to various PCR techniques (e.g., qPCR, RT-qPCR), isothermal amplification (qLAMP, RT-qLAMP), and nucleic acid isolation and manipulation.
  • Design primers for use in molecular assays and ensure their specificity and efficiency.
  • Conduct experiments to validate assay performance and troubleshoot issues as needed.
  • Analyze and interpret complex data sets to guide the development and optimization of assays.
  • Support translation of ultra-rapid chemistries from the bench top to a microfluidic device.
  • Collaborate with cross-functional teams, including product development, manufacturing and quality control, to integrate assay development with product pipelines.
  • Maintain a detailed research log and summarize work in research reports and presentations.
  • Present research findings, project updates, and technical information to internal and external stakeholders.
  • Stay up to date with the latest advancements in molecular biology and related fields to incorporate innovative approaches into assay development.
  • Mentor and provide technical guidance to junior scientists and research associates.

QUALIFICATIONS:


  • Ph.D. in Molecular Biology, Biochemistry, Genetics or related field with a minimum of 2-4 years industry R&D experience.
  • In-depth knowledge and hands-on experience with a broad range of molecular biology techniques, including but not limited to, various PCR techniques, Loop-mediated isothermal amplification (LAMP) and nucleic acid isolation and manipulation, and primer design.
  • Strong analytical skills with the ability to interpret and present complex data effectively.
  • Strong attention to detail, self-motivation, good organizational skills, ability to prioritize and multi-task, and able to work both independently and as part of a team
  • Experience with automation and high-throughput assay development is a plus.
  • Experience working with clinical samples.

KNOWLEDGE, SKILLS, AND ABILITIES:


  • Knowledge of DOE-based assay optimization is a plus
  • Prior work with microfluidic systems is a plus
  • Comfortable working in a BSL2 environment
  • Proven interpersonal, communication, and presentation skills
  • Proficient with Microsoft office suite of programs
  • Proficient with one or more common graphical analysis software(s) (RStudio, Graphpad Prism, Minitab, etc.)

COMPENSATION AND CLASSIFICATION:


  • Classification: Full-time position
  • Compensation: Package is competitive/commensurate with experience
  • Benefits: Medical insurance
  • Location: Lisbon, Portugal

This job is no longer open

Life at Inflammatix

Inflammatix, Inc. is a venture-backed startup located in the San Francisco Bay Area that is building novel diagnostics for acute infections and sepsis based on our unique immune biomarkers. Approximately $10 billion / year is spent trying to diagnose acute infections, but current technologies that focus on ᅢᄁ¬ツᆲᅨワfinding the bugᅢᄁ¬ツᆲ¬トᄁ are (1) slow and (2) effective in fewer than 30% of cases. Inflammatixᅢツᅡᅠhas developed a statistically rigorous,ᅢツᅡᅠextensively validated diagnostic method that 'reads' the immune system. Our HostDxᅢᄁ¬ダᅡᄁ tests report clinically actionable information on theᅢツᅡᅠpresence, type (bacterial or viral), and severity of infection in all patients. They have been extensively validated and published in top-tier medical journals. After this initial product, Inflammatix plans to develop and commercialize additional novel diagnostic tests to address significant unmet clinical needs.
Thrive Here & What We Value* Equal opportunity employment* Diverse benefits package (medical, dental, vision insurance; HSA, FSA, commuter, LTD, STD and basic life insurance)* Retirement plan with employer match (401k)* Paid winter break for U.S. salaried/exempt employees
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