About InduPro
InduPro, Inc. is bringing life-changing therapies to patients through novel cell-surface platform technologies. We are defining and manipulating protein interactions beyond natural signaling paradigms. InduPro platforms integrate inherent protein proximity at the cell surface with the ability to manipulate protein pairings via induced protein proximity to create novel signaling pathways and logic gates. Our culture fosters innovation at every level.The OpportunityWe are seeking a talented and motivated Scientist II to join our In Vivo Pharmacology research team.
As an integral part of our drug discovery efforts, you will contribute to the strategy and evaluation of novel compounds using in vivo mouse models of inflammation and oncology. If you're passionate about advancing drug development, have a strong scientific background in immunology, and have hands-on experience with animal studies, we'd love to hear from you!
Key Responsibilities
- Provide in vivo pharmacology leadership for one or more projects in InduPro’s preclinical pipeline (inflammation and/or oncology).
- Develop and implement in vivo and ex vivo models, including humanized models, to investigate the activity of novel antibody-based therapeutics in disease-relevant settings.
- Design and execute in vivo experiments to assess drug efficacy, safety, pharmacokinetics and mechanism of action.
- Perform dosing (oral, subcutaneous, intraperitoneal, and intravenous), blood collection, and tissue sampling in mouse models.
- Lead ex vivo immunophenotyping and functional characterization by multiparameter flow cytometry, ELISA, and cell-based assays.
- Analyze complex datasets, interpret results, and collaborate with cross-functional teams, including CROs.
- Write IACUC and study protocols, study reports for regulatory filings, and contribute to scientific publications.
- Ensure compliance with ethical guidelines and regulatory requirements.
Supervisory Responsibilities
- None (potential for managing up to 1 direct report)
Other Skills & Abilities
- Strong critical thinking and analytical skills, proficiency in data analysis tools, and excellent communication skills.
- Demonstrated ability to manage research projects within cross-functional teams.
- Enthusiasm for learning new techniques and how to design and characterize new in vitro and in vivo experimental systems.
Education & Experience
- PhD or equivalent in pharmacology, immunology, or related field with 2+ years of post-graduate experience in the field.
- Hands-on experience with animal handling and in vivo studies in mouse models.
Preferred Experience
- Proven track record utilizing humanized in vivo models for inflammatory diseases and/or oncology, preferably with industry experience in pharmaceutical or biotech settings.
- Strong expertise in human immune cell phenotyping by multiparameter flow cytometry.
Physical Work Requirements
- Prolonged periods standing, reaching and bending while working in the lab.
- Prolonged periods sitting at a desk and working on a computer.
- Physical presence at the InduPro worksite, or in the field, is required for this role.
Travel Requirements
- This position does not generally require travel.
$120,000 - $150,000 a year
Benefits
At InduPro we believe that being face to face helps enhance collaboration, innovation, productivity, employee well-being, employee engagement, and Company culture. Every member of the InduPro team plays a role in shaping our science and our culture in a dynamic startup environment. We offer a competitive total compensation package, including stock options, participation in an annual performance bonus incentive program, a comprehensive benefits package, paid time off, and exciting opportunities for professional development.Benefits include medical, dental, and vision coverage; company-paid life and disability insurance; supplemental life and disability insurance; voluntary accident, critical illness, and hospital indemnity insurance; a 401(k) plan with employer matching contributions; flexible spending accounts; an employee assistance program; flexible paid time off; 10 paid company holidays; and employee access to voluntary auto, home, legal, and pet insurance.InduPro, Inc.
is an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, age, gender identity, sexual orientation, color, religion, sex, marital status, national origin, protected veteran status, disability, or any other status protected by federal, state, or local law.Apply for this job
