ApplyJob Type
Full-timeDescription
Position Title:
Senior Manager, Project Management
Reports to:
Head of Project Leadership
Location:
This role may be hybrid, located within commuting distance to Philadelphia, PA, or Boston, MA, and requires the ability to travel domestically and internationally (~20%)
Company Background:
Century Therapeutics is an innovative biotechnology company that is building an industry-leading allogeneic iPSC-derived cell therapy platform that integrates cutting-edge gene editing, protein engineering, technical development, and manufacturing capabilities to generate allogeneic, iPSC-derived NK and T cell therapies for cancer and autoimmune and inflammatory diseases. Century’s foundational technology is built on induced pluripotent stem cells (iPSCs) that have unlimited self-renewing capacity.
This enables complex cellular engineering to produce controlled cell banks of modified cells that can be expanded and differentiated into desired immune effector cells, which can supply vast amounts of allogeneic, homogeneous therapeutic products. This platform differentiates Century from other approaches that utilize non-renewable donor-derived cell products for the treatment of cancer and autoimmune and inflammatory diseases with significant unmet medical needs.
Role:
This position reports directly to the Head of Project Leadership. The candidate will facilitate and manage cross-functional drug development teams through preclinical and clinical phases, focused on the development of Century’s novel iPSC-derived allogeneic iNK and iT cell therapies in oncology and autoimmune indications. S/he will guide teams for Century’s pipeline projects to successfully progress deliverables, timelines, and budgets, in collaboration with functional leads. S/he will be a driver of project management, portfolio, and governance excellence for Century.
Responsibilities:
- Drive and manage allogeneic iPSC-derived targeted cell therapy therapeutic development projects in hematology, oncology, and autoimmune diseases, from preclinical development through clinical proof of concept, in collaboration with cross-functional project teams.
- Facilitate Drug Candidate selection-enabling, with familiarity in the research phase, IND-enabling & clinical Phase I/II-enabling activities, including nonclinical safety, CMC, translational, regulatory, clinical, and clinical operations activities.
- Strategic leadership to analyze scenarios and define options for programs.
- Along with functional leads, drive program strategy and decision-making, considering the impact on timelines, resources, and budget.
- Independently lead sub-teams reporting through the project team.
- Develop, own, and manage timelines and team tools.
- Identify project risks and issues; work with functional experts to mitigate and resolve them.
- Develop and coordinate resource and budget planning.
- Prepare agendas, minutes, and progress reports.
- Communicate effectively across all functional areas so that deliverables and interdependencies are clear.
- Ensure high-performing teams.
- Responsible for >1 pipeline project across indications.
- May directly manage alliance programs and serve as the point of contact with partners.
- Ensure that all activities comply with company SOPs, GxPs, and any regional-specific regulations.
- Define, recommend, and implement project management operational needs.
Qualifications:
- Bachelor’s degree in science or engineering required. Advanced degrees are desirable (MS, MBA, PharmD, or PhD).
- +8 years of relevant biopharmaceutical experience.
- A minimum of 5 years of project management in a cross-functional drug development or team role is required.
- PMP certification preferred.
Requirements:
- Direct project management experience in a therapeutic drug development setting in hematology, oncology, or autoimmune disease areas.
- Project management experience from IND-enabling phase to Phase I/II clinical studies.
- Experience in cell therapies, gene therapy, biologics, or vaccine development.
- Familiarity with regulatory requirements (e.g., FDA regulations, and ICH /GxP guidelines), technical (CMC) requirements, and clinical study execution.
- Alliance management or collaboration experience desired.
- Excellent project management, communication, and cross-functional collaboration skills, with a results-driven mindset.
- Able to motivate and develop individual team members and overall team performance.
- Proven ability to effectively manage conflicts and negotiations while providing impact and influence.
- Excellent organizational, analytical, and planning skills.
- Robust proficiency in project management and collaboration support tools and systems.
- Strong initiative and “can do” attitude, and dedicated work ethic.
- Experience with industry-standard project management timeline and tracking tools (MS Project, Smartsheet) preferred.
Century Therapeutics Inc. is an Equal Employment Opportunity/Affirmative Action Employer - Minority/Female/Disability/Veteran. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, veteran status, or any other characteristic protected by federal, state, or local law.
