The field of gene therapy is growing rapidly and Genezen is here to meet the exacting needs of our clients. We provide process development, produce GMP viral vectors, and provide cell transduction for gene and cell therapy clinical trials and are proud to be a part of the process that leads to new cures.
WORKING AT GENEZEN
Many people have worked in environments where you feel like just another nameless part of an enormous machine. Genezen is different. We want our employees to be innovative, collaborative problem solvers who are dedicated to meeting the challenges of working at a fast-growing company. We are dedicated to empowering our employees to be their best and making Genezen a rewarding place to work. Every employee contributes to the success of the company and you can be part of that team.
PURPOSE
We are looking for someone with high emotional intelligence and is comfortable working closely across the team to join us in facilitating the production of viral vectors. The Laboratory Associate I/II will be needed to perform analytical assays for viral vector process development, assist with method development, document experiments, help with lab maintenance and execute assay qualifications. This position calls for an independent thinker who can work seamlessly in a matrixed environment.
ESSENTIAL JOB FUNCTIONS
- Execute assays involved in viral vector characterization using modalities like flow cytometry, ddPCR, ELISA and cell culture.
- Perform experiments related to lentivirus, retrovirus and AAV platforms.
- Assist with in-lab and out of lab (e.g., report writing) activities to develop methods and qualify assays per ICH guidelines.
- Work closely with lead scientists to address items such as client comments and concerns.
- Maintain appropriate documentation of processing activities, including quality. control of written and electronic data.
- Assist with sample management for process development and clients.
- Handle and track lab materials and inventory.
- Help engage with new technology evaluations and to incorporate new platforms.
- Perform routine lab maintenance and maintenance of laboratory equipment.
- Train new staff members and fellow employees in designated processes as directed by lead scientists.
- Work across functions like manufacturing, QA and supply chain as needed.
- Contribute to the maintenance of laboratory equipment and laboratory support operations.
- Comply with all established policies and SOPs.
- Properly maintain laboratory notebooks, raw and analyzed data and client records in timely manner.
- Adaptability required as work schedule may change based on business needs.
- Criminal background check required.
- Other duties as assigned.
KNOWLEDGE, SKILLS AND EXPERIENCE
- Associate, BS or MS degree in Biology, Biochemistry, Molecular Biology, or similar field.
- 1 - 5 years of relevant industry/lab experience in a biopharma and/or CDMO industry setting.
- Hands-on experience with molecular biology techniques required, such as PCR, ELISA and cell culture.
- Flow cytometry greatly desired. BSL 2/2.5 environment, cell culture, and molecular biology.
- Previous experience working with gene therapy vectors and protein or vector production and/or purification.
- Excellent computer, verbal, and written communication skills.
- High level of organization; detail oriented.
- Analytical thinking and problem-solving capabilities.
- Precision pipetting.
PHYSICAL DEMANDS
The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.Work Environment
- Frequently required to work in a BSL 2 environment with personal protective equipment/aseptic gowning
- Regularly required to work around large machinery and typical utilities seen in pharmaceutical facilities
- Occasionally exposed to moving mechanical parts; high, precarious places; toxic or caustic chemicals; hazardous waste; and risk of electrical shock
- Occasionally exposed to extremely loud noise levels
- Spending time on the floor during activity execution (maintenance, construction, commissioning and qualification) is required Movement
Movement
- Frequently required to stand; sit; use hands to finger, handle, or feel; reach with hands and arms
- Occasionally required to walk; climb or balance; and stoop, kneel, crouch, or crawl Lifting
Lifting
- Frequently lift and/or move up to 10 pounds • Occasionally lift and/or move up to 25 pounds Vision
- Frequently utilize close vision and the ability to adjust focus Communication • Frequently required to communicate by talking, hearing, using telephone and email
Vision
- Frequently utilize close vision and the ability to adjust focus Communication
Communication
- Frequently required to communicate by talking, hearing, using telephone and email
GENEZEN'S CURES VALUE-BASED COMPETENCIES
Committed to ScienceWe are committed to scientific excellence, staying current with industry developments, making data-driven decisions, and pursuing innovation to advance healthcare.Urgency in action for the patientsWe operate with urgency and a commitment to delivering timely treatments to patients by accelerating our partners' programs.Resilience & Grit in operationsWe are committed to overcoming challenges, learning from failures, and persistently striving for success. Execute with Excellence & IntegrityWe are dedicated to delivering quality results and upholding ethical principals.Solutions driven for our partnersWe are committed to being a proactive, collaborative, creative and open-minded partner.
GENEZEN'S BENEFITS
- Paid vacation days, amount based on tenure
- Paid sick time
- 9 observed holidays + 1 floating holiday + 1 volunteer day
- 401(k) plan with company match up to 6% of salary, vested immediately
- Share Appreciation Rights
- Choice of several healthcare plans
- FSA and HSA programs
- Dental & vision care
- Employer-paid basic term life/personal accident insurance
- Voluntary disability, universal life/personal accident insurance
- Accidental Death & Dismemberment (AD&D) Insurance
ADDITIONAL DETAILS
- Nothing in the job description for this role restricts management’s right to assign or reassign duties and responsibilities to this job at any time.
- This position requires a criminal background check.
- Genezen is an Equal Opportunity Employer.
- Genezen participates in EVerify.
- Genezen is interested in every qualified candidate who is eligible to work in the United States; however, we are not able to sponsor visas.
Genezen has operates two locations: one in Fishers, Indiana and the second in Lexington, Massachusetts. Fishers is a suburb of Indianapolis. Fishers was named the #1 place to live in the US by Money Magazine in 2017 for its livability, safety and entrepreneurship. Fishers is one of the fastest growing communities in Indiana and is dedicated to supporting a high quality of life for all its residents. Nearby Indianapolis is home to professional and college sports teams, the Indy 500, a growing art community and the world’s largest children’s museum--to name just a few reasons why this area is a great place to live.Lexington, Massachusetts, located just northwest of Boston, is renowned as a historic suburb with a rich cultural heritage.
It boasts picturesque New England charm, tree-lined streets, and a vibrant community. Known for its pivotal role in the American Revolution, Lexington offers visitors and residents alike a blend of historical landmarks, modern amenities, and a strong sense of community pride.
