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Director of Immunology

GenEditSouth San Francisco, California, United StatesOnsite
This job is no longer open
GenEdit is a rapidly growing, early-stage company that is developing a proprietary and novel delivery platform with the potential to transform genetic medicine. Our interdisciplinary team works together across chemistry, payload, formulation, screening, and preclinical groups to develop the next generation of gene therapies. GenEdit fosters an exciting and dynamic environment where we value impactful data and creative solutions to accelerate our progression from platform technology to a pipeline of therapeutic candidates. We are seeking talented and motivated individuals to join our team and are expanding across all functions within the organization. Join us in South San Francisco, CA, to be at the forefront of the future of gene therapy.
We are seeking a Director of Immunology to join our cross-functional discovery teams and create novel drug candidates.

Key Responsibilities


-Drive internal and external partnered research from new target identification and technology platform development to create therapeutic opportunities for patients with autoimmune and inflammatory diseases.-Function as the key project leader of multi-functional scientific teams and ensure successful and timely execution of one or more preclinical research programs.-Be a strong scientific thinker with considerable experience leading the discovery and development of therapies for immunological diseases.-Lead the identification of novel innovative inflammation drug discovery and developmental science through the preclinical pipeline in support of candidate selection.-Interface with senior leadership, alliance management, and the business development group and review innovative external opportunities.-Be a highly collaborative and energetic scientist and leader with superior communication skills, who can balance multiple, collaborative projects and act as a senior scientific consultant to and leader of early-stage matrixed project teams.

Qualifications


-PhD degree in Immunology or a closely related discipline with 10+ years of experience-6 years desired minimum industry experience-2 years minimum management experience ideally as a research project leader focused on strategic external collaborations.-Experience developing and evaluating novel nanoparticle or nucleic acid therapeutics for immune therapeutics is highly desirable.-Desired technical skills:·Highly knowledgeable and experienced in all aspects of drug discovery and development for Inflammatory or autoimmune diseases through proof of concept.·Experienced with validation of drug targets and the exploratory drug development process with a proven track record.·Extensive experience developing and/or evaluating novel small molecule, biologic or nucleic acid therapeutics.·Excellent written and verbal communication skills in English.

-Desired behavioral competencies:·Forward thinking with the ability to recommend, influence and implement organizational change and continuous innovation.·Ability to build strong relationships and collaborate effectively with other interfacing GenEdit functions. ·Comfortable challenging the status quo and bringing forward innovative solutions.·Ability to take risks implementing innovative solutions.·Proven skills as an effective team player who can engender credibility and confidence within and outside the company.Apply for this job

This job is no longer open

Life at GenEdit

GenEdit is a next-generation genome editing company. We are developing non-viral delivery technologies for the CRISPR/Cas9 gene editing system that can safely and efficiently correct gene mutations in patients. CRISPR/Cas9 is a powerful genome editing tool that makes therapeutic gene editing possible. It is easier to use, faster, and more accurate than previous gene editing techniques and thus has the potential for a wide range of therapeutic applications. In particular, CRISPR/Cas9 gene editing has the potential to treat a variety of incurable genetic diseases. However, current CRISPR delivery methods rely on viruses and are problematic due to viral-induced toxicity and prolonged Cas9 exposure, increasing off-target effects. A non-viral CRISPR/Cas9 delivery method is needed. In addition, low efficiency levels achieved make it impossible to target certain diseases. GenEdit's novel CRISPR delivery technology has the potential to be a platform delivery system for a broad range of genetic diseases. We also work on engineering of core components of CRISPR/Cas9 genome editing system to increase editing efficiency and enable targeted delivery.
Thrive Here & What We Value1. Dynamic and exciting environment2. Valuing impactful data and creative solutions3. Emphasis on teamwork and collaboration4. Commitment to advancing novel therapies in genetic medicine5. Diversity as a strength6. Inclusive hiring practices
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