About Madrigal:
Madrigal is a biopharmaceutical company pursuing novel therapeutics for non-alcoholic steatohepatitis (NASH), also known as metabolic dysfunction associated steatohepatitis (MASH). Our first therapy, Rezdiffra (resmetirom), was granted accelerated approval by the U.S. Food and Drug Administration (FDA) for the treatment of adults with NASH with moderate to advanced liver fibrosis (consistent with stages F2 to F3 fibrosis) and is being studied in a Phase 3 trial for the treatment of NASH with compensated cirrhosis.
Role Overview:
The Director Medical Affairs Strategy is responsible for developing and executing strategic medical plans and providing scientific and medical expertise to support those plans including, but not limited to lifecycle management, investigator-initiated studies, scientific platform and lexicon and medical education. Reporting to the Vice President, Global Medical Affairs Strategy, the Director, Medical Affairs Strategy serves as the subject matter expert to create the indication-specific or product-specific Medical strategic framework and prioritized Medical Affairs tactics to ensure the success of resmetirom throughout the product lifecycle.
This individual will bring together strong technical knowledge of the therapeutic area, strong command of the relevant clinical practice guidelines and related scientific data. In partnership with the VP, Medical Strategy, this role develops medical strategy in close collaboration with R&D, Medical Directors within Scientific Communications, Field Medical and Medical Excellence to support the department and organizational objectives.
Position Responsibilities:
- Develop and Execute Medical Affairs Strategy:
- Strategically develop and execute Medical Affairs plans, ensuring alignment with the company’s overall business goals including the brand team.
- Create tactical plans for the company’s therapeutic area, adhering to regulatory requirements and Standard Operating Procedures (SOPs).
- Identify unmet medical needs and strategic insights and complete situational analysis to guide the company's medical and scientific priorities.
- Manage Product Lifecycle:
- Contribute to the development and execution of the lifecycle plan of resmetirom, from development through commercialization and post-market activities, ensuring alignment with strategic goals and regulatory requirements.
- Identify and implement opportunities for product enhancements, optimization, and updates based on market feedback, performance metrics, and evolving industry standards.
- Develop and execute an Investigator Initiated Study program and collaborate cross-functionally to deliver Phase 4 clinical studies.
- Work with Medical Operations to stand up and execute a best-in-class IIS program. Lead the evaluation and decision-making process on grant submissions.
- Work in a collaborative manner to execute Phase 4 studies delivering against the Life Cycle Management and Brand plans.
- Medical Product Team:
- Actively participate in the cross-functional team in the development and management of resmetirom, ensuring compliance, strategic alignment, and timely delivery with the medical strategy.
- Define key strategies and initiatives to support global asset and company goals.
- Engage with Key External Stakeholders:
- Act as an external interface with stakeholders including clinicians, insurers, government leaders, professional societies, and medical-scientific institutions.
- Ensure engagement with the medical community through scientific advisory boards, stakeholder engagements, webinars, and presentations.
- Serve as a spokesperson for the company in scientific forums and with healthcare professionals.
- Collaborate across Functions: Partner with R&D, Market Access, regulators, Commercial and Brand Team to ensure alignment with the company’s overall business goals.
- Medical Expertise and Leadership: Provide strategic leadership and medical expertise to guide the development and implementation of clinical programs, ensuring alignment with regulatory standards and organizational goals.
Qualifications and Skills Required:
- Bachelor’s Degree and advanced scientific/healthcare degree required (e.g., MD, PharmD, PhD, MS, etc.)
- Minimum 8 years in the pharmaceutical industry including previous experience in developing and executing against a medical strategy including investigator-initiated study programs
- Strong track record of written and oral communication skills to develop and present medical strategies to varied audiences and articulate messages succinctly
- Understands detailed technical information and conveys complex ideas to a variety of audience types and cultures
- Strong organizational skills to track numerous tasks for multiple simultaneous projects in a deadline-oriented environment
- Role is based in Conshohocken, PA. Incumbent must be able to commute into the office per our hybrid work policy. (3 days per week)
- Ability to travel up to 10% of the time to medical congresses, both domestic and international
Compensation:
Base salary is determined by several factors that include, but are not limited to, a successful candidate's qualifications, skills, education, experience, business needs, and market demands. The role may also be eligible for bonus, equity, and comprehensive benefits, which include flexible paid time off (PTO), medical, dental, vision, and life and disability insurance.Madrigal is an Equal Opportunity Employer. All employment is decided on the basis of qualifications, merit, and business need. Applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex gender identity, sexual orientation, national origin, age, disability, protected veteran or disabled status, or other characteristic protected by applicable federal, state, or local law.Unsolicited resumes from agencies should not be forwarded to Madrigal.
Madrigal will not be responsible for any fees arising from the use of resumes through this source. Madrigal will only pay a fee to agencies if a formal agreement between Madrigal and the agency has been established.Please be aware that we are currently receiving numerous reports of individuals misrepresenting themselves as Madrigal Pharmaceuticals’ Hiring Managers, seeking to engage with job candidates through fraudulent online advertisements or job posting sites. These unauthorized individuals are using Madrigal’s name and logo in an attempt to solicit up-front fees and obtain personal information from interested job candidates.
Please know that Madrigal does not conduct interviews via text or in chat rooms; conduct interviews via Skype, RingCentral or solely via telephone; charge candidates an advance fee of any kind (e.g., fees for purchasing equipment); nor does it offer positions of employment without undergoing a thorough recruiting process. Interviews with Madrigal are conducted via the Zoom platform.Please also note that any correspondence with regard to employment would come from an authorized madrigalpharma.com email address or from an email address from one of our trusted search firm partners.
We are aware that incorrect/fraudulent email addresses, with Madrigal misspelled, have been utilized in these most recent fraud attempts. If you receive unsolicited employment offers from people claiming to work for Madrigal we recommend that you: do not respond to their questions; do not open any attachments; and do not click on any hyperlinks.
