Passionate about precision medicine and advancing the healthcare industry?
Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.We are looking for a highly skilled Research Scientist to join our Biological Modeling team to support Organoid Based Screening. Our CAP accredited facility develops human tumor models for use in a range of studies with our academic and commercial partners to discover next-generation cancer therapies.
The ideal candidate will have a strong understanding of molecular gene editing, fluorescent imaging, image analysis, protein detection, and cell culture techniques. Post-doctoral and/or industry experience employing human organoid tissue models in high-throughput formats is preferred.The successful candidate must be able to work in a fast-paced multidisciplinary environment and will be expected to communicate results both internally and to commercial partners.
What You’ll Do:
- Work in a collaborative, interdisciplinary team of scientists employing gene-editing approaches to perturb cellular pathways with the aim of identifying therapeutic targets
- Design and execute high-throughput gene-editing, imaging, and protein detection workflows
- Culture primary human tissue samples
- Work with automated liquid and plate platforms at all stages of development
- Execute sequencing studies end-to-end
- Develop analysis pipelines to process and visualize large high-throughput data sets
- Generate summary reports of screening results and molecular data for customer deliverables
Qualifications:
- Ph.D. in oncology, molecular systems biology, or a related field
- 1+ years of industry or post-doctoral experience
- Experience with 3D tissue models preferred, general cell culture experience is a must
- Experience generating and assessing next-generation sequencing data is preferred
- Proficiency in R and/or Python strongly preferred
- Experience with brightfield and fluorescent microscopy
- Experience coordinating complex experimental workflows across multidisciplinary teams
- Previous experience developing methods for and/or operating automated liquid handlers (Biomek, Echo, etc.)
Benefits:
- Competitive salary and benefits package
- Collaborative and supportive work environment
- Chance to make a real impact on the healthcare industry
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We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.Additionally, for remote roles open to individuals in unincorporated Los Angeles – including remote roles- Tempus reasonably believes that criminal history may have a direct, adverse and negative relationship on the following job duties, potentially resulting in the withdrawal of the conditional offer of employment: engaging positively with customers and other employees; accessing confidential information, including intellectual property, trade secrets, and protected health information; and appropriately handling such information in accordance with legal and ethical standards.
Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law, including the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.
