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People Operations Manager, Benefits and HRIS (Contract)

Maze TherapeuticsSouth San Francisco, California, United StatesOnsite

The Position:


We are seeking a People Operations Manager to join us onsite at our Maze headquarters for a contract position to cover parental leave. In this temporary onsite role, you will support Maze People Operations by serving as the HRIS (ADP) lead, guiding new hires through onboarding, maintaining employee data, and act as the central resource for benefits administration. Reporting to our Senior Manager of People Operations, you will help administer policies, programs, and build employee connection through assisting our culture committee’s monthly company-wide events.

Your Impact:


  • Benefits Administration:
  • Administer Maze’s benefits programs, including systems, communications, and enrollment
  • Serve as primary support resource to employees on benefits-related matters by interpreting policies and leveraging resources
  • Ensure that leave programs are administered accurately, consistently and uniformly in line with established policies and procedures including applicable laws and regulations, and serve as the point person for our employee leave of absence concierge
  • Monitor benefit enrollments, terminations, changes in coverage and audit as necessary
  • HRIS / Data:
  • Continuously update and monitor new hires, terminations, changes in reporting structures and organizational changes and execute through our HRIS platform (ADP Workforce Now) and internal org chart (Pingboard)
  • Liaise with our finance team to support critical processes such as payroll, accounts payable, purchasing, HR budgeting, etc. 
  • Execute on company-wide compliance initiatives and support People Operations related ad-hoc projects
  • Employee Experience:
  • Create a positive onboarding experience by conducting new hire benefits orientation and manage a smooth employee offboarding process
  • Support Maze’s culture committee by working collaboratively with key stakeholders to help execute monthly cultural events and initiatives, and oversee the committee’s budget

Skills and Qualifications:


  • Bachelor’s degree in Human Resources or related field or equivalent experience
  • 5+ years Human Resource experience working in a small to mid-sized company or start-up environment
  • Experience administering corporate benefit programs
  • Experienced in HRIS administration and reporting in ADP
  • Meticulous attention to detail with effective organization and communication skills
  • Proven ability to handle sensitive and confidential information with discretion and sound judgement
  • Demonstrated problem solver with a systems-thinking mindset
  • Self-motivated attitude with a collaborative spirit; a team player who has a growth mindset and ability to conduct self-directed work
  • Demonstrated flexibility and professionalism in managing conflicting priorities and anticipating needs
  • Proficiency in Microsoft Office Suite, including Word, Outlook, Excel, and PowerPoint

About Maze Therapeutics


Maze Therapeutics is a clinical-stage biopharmaceutical company harnessing the power of human genetics to develop novel, small molecule precision medicines for patients living with common diseases, with a focus on renal, cardiovascular and related metabolic, including obesity. The company is advancing a pipeline using its Compass platform, which provides insights into the genetic variants in disease and links them with the biological pathways that drive disease in specific patient groups. The company’s pipeline is led by two wholly owned lead programs, MZE829 and MZE782, each of which represents a novel precision medicine-based approach for chronic kidney disease.  Maze is based in South San Francisco. 

Our People


Maze is comprised of a team of passionate and creative professionals committed to discovering and delivering transformative medicines to patients suffering from both rare and common genetic diseases. We are fostering a culture that encourages vision, initiative and the development of talent. Our supportive work environment inspires creative thinking and freedom of expression, resulting in a stimulating atmosphere where people enjoy coming to work. While we have a passion for advanced science and pride ourselves on excellence in execution, ultimately, everything we do is about patients. 

Our Core Values


Further Together – Our path is paved with challenges, but with resilience and a team-first mentality, we’ll achieve our mission.  


Impact Obsessed – We embrace the bold, take calculated risks, and learn from our mistakes to improve the lives of others. 


Stand True – Our integrity is foundational; it guides us no matter the obstacle. 


Life at Maze Therapeutics

Maze Therapeutics is translating novel genetic insights into lifesaving medicines, through an approach that integrates human genetics and functional genomics. Advances in these areas have enabled us to decode the mysteries of genetic modifiers in a range of severe diseases, which we aim to turn into medicines that mimic protective mutations. We have assembled a world-class team that we need to realize this vision, including creative scientific pioneers in genetics, experienced company builders, and biotech industry leaders.
Thrive Here & What We Value1. Vision, initiative, talent development2. Bold ideas, calculated risks for patient improvement3. Team collaboration and shared mission4. Integrity-guided decision making5. Inspiring creativity and freedom of expression in work environment6. Genetically informed therapies focus7. Advanced data science integration8. Proprietary Maze Compass Platform™ for variant functionalization9. Broad portfolio development through owned and partnered programs10. Commitment to transforming lives with precision medicines
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