About Us:
Ambience is developing the most capable AI systems for healthcare and medicine. As healthcare costs soar to 17.3% of US GDP and a projected shortage of 100,000 physicians within the next decade, the need for AI is critical. Our frontline healthcare workers are overwhelmed, with only 27% of the average clinician's day spent on direct patient care.Our vision is to equip every healthcare worker with an advanced AI co-pilot. We believe that people, augmented by AI, will enable us to deliver higher quality healthcare at a lower cost, improving the experience for everyone involved.Headquartered in San Francisco, we have secured $100M in funding from top investors, including Kleiner Perkins, OpenAI Startup Fund, Andreessen Horowitz, Optum Ventures, Human Capital, and Martin Ventures.
We collaborate with leading AI experts such as Jeff Dean, Richard Socher, Pieter Abbeel, and AIX Ventures.Join us in the endeavor of accelerating the path to safe & useful clinical super intelligence by becoming part of our community of problem solvers, technologists, clinicians, and innovators.
The Role: VP of Security
As VP of Security at Ambience, you will be entrusted with defining, driving, and continuously enhancing our security strategy. You will manage enterprise risk, ensure compliance across regulatory frameworks, and maintain a robust security posture that supports our rapid growth. This role is both highly strategic and hands-on, requiring you to collaborate across the company—from engineering and product to sales and legal—to embed security best practices, mitigate risks, and instill a culture of security and privacy.
This position reports directly to our executive leadership.
What You'll Do:
- Risk Management & Leadership
- Expand and refine our Risk Registry and Security Posture
- Translate risks into clear OKRs and resource needs
- Security Operations
- Set and manage security budgets every six months, optimizing costs
- Build and lead a high-performing security team, including hiring and development
- Oversee ad hoc security tasks (infrastructure approvals, IR/BCDR plans, etc.) with transparent documentation
- Compliance & External Communication
- Determine adoption timelines for key frameworks (HITRUST, ISO, FedRAMP)
- Develop and maintain policies on technical security, data privacy, sharing, and HIPAA
- Collaborate with sales, legal, and customer teams to support client-facing security requirements and contract documents
Who You Are:
- Seasoned Security Leader
- 7+ years in security-critical environments (healthcare, finance, federal, or security tech)
- Experience in enterprise SaaS and small-to-mid-size startup settings
- Has managed and scaled security teams (Director/VP-level a plus)
- Strategic & Hands-On
- Adept at prioritizing risks, building action plans, and communicating trade-offs
- Comfortable working directly with technical teams to drive alignment and execution
- Mission-Aligned
- Drawn to healthcare innovation, motivated by improving clinician and patient outcomes
- Thrives in a fast-paced, early-stage environment, ready to take on new challenges proactively
Compensation
$250,000 - $300,000, with the addition of meaningful equity.
Are you outside of the range?
We encourage you to still apply; we take an individualized approach to ensure that compensation accounts for all of the life factors that matter for each candidate.
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Being at Ambience:
- An opportunity to work with cutting edge AI technology, on a product that dramatically improves the quality of life for healthcare providers and the quality of care they can provide to their patients
- Dedicated budget for personal development, including access to world class mentors, advisors, and an in-house executive coach
- Work alongside a world-class, diverse team that is deeply mission aligned
- Ownership over your success and the ability to significantly impact the growth of our company
- Competitive salary and equity compensation with benefits including health, dental, and vision coverage, paid maternity/paternity leave, quarterly retreats, unlimited PTO, and a 401(k) plan
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