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Sr. QC Analyst

Dyno TherapeuticsWatertown | Massachusetts, United StatesOnsite

The Role


Sr. Quality Control Analyst. You will play a key role in the execution and communication of routine AAV production quality control assays. Your work will directly impact the success of our capsid discovery and validation efforts, ensuring that all studies are conducted with well-characterized AAV preparations. You will also contribute to the continual enhancement of our vector production processes, driving efficiency and quality improvements that minimize time to study while achieving the highest standards in AAV preparation.Job Type: Full TimeLocation: Watertown, MA

How You Will Contribute


As Sr. Quality Control Analyst you will be responsible for executing and communicating results for a variety of AAV quality control assays, including ddPCR titration, Silver Stain, ELISA, and potency assays. You will work collaboratively to ensure timely delivery of vector production QC data and help refine and develop new assays to ensure continuous improvement in production processes.Responsibilities: 

  • Execute current AAV Production Quality Control assays, particularly ddPCR titration, with strong attention to detail and clear communication of results.
  • Ensure timely delivery of QC data, meeting predefined turnaround times.
  • Collaborate with the QC Lead to optimize and improve existing assays.
  • Assist in development of new QC assays (e.g. novel potency assays).
  • Contribute to maintaining well-defined and easy-to-use QC sample submission and data reporting processes.

Basic qualifications


  • BS or MS in biology, biochemistry, biomedical engineering, or related fields.
  • 2+ years of experience running quality control assays for AAV productions, including ddPCR, Silver Stain, ELISA, and potency assays.
  • Proven ability to effectively communicate QC results to both technical and non-technical stakeholders.
  • Strong understanding of the assays being performed and a demonstrated ability to troubleshoot assay issues.
  • Alignment with Dyno’s core values.

Preferred qualifications


  • Prior experience working in an industry based setting.
  • Experience in developing capsid characterization assays.

The Company


At Dyno Therapeutics, we are a forward-thinking team on a mission to build high-performance genetic technologies that transform patient lives. Our team unites world-class molecular biologists, protein engineers, software developers, data scientists, and machine learning experts—all working together to shape the future of gene therapy.Our culture is defined by three core values:

  • One Mission: Everything we do is for the mission. We are a cohesive and motivated team, thinking ahead and supporting one another to overcome challenges.
  • Proactive Responsibility: We take action, inject energy into our work, and hold ourselves accountable for delivering results.
  • Reaching for Excellence: We constantly strive for excellence, fueled by curiosity, adaptability, and the courage to speak hard truths in pursuit of success.

These values are more than words—they guide our daily actions. We seek individuals who share our passion for innovation, excellence, and teamwork. At Dyno, building life-changing technologies isn’t just a job; it’s a mission that drives us forward.

Equal Employment Opportunity (EEO) Statement


We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

Fraud Alert:

 Please be aware of recruitment scams targeting job seekers. Dyno Therapeutics will never make an offer of employment without conducting a formal interview process, nor will we ask for personal information such as financial details over email. Official communication will only come from an @dynotx.com email address. If you are contacted by someone claiming to represent Dyno Therapeutics from any other domain, please report it as spam and report the communication to us at jobs@dynotx.com.

Life at Dyno Therapeutics

Dyno Therapeutics is a Cambridge based, VC-backed biotech startup that uses next-gen DNA technologies and machine learning to engineer Adeno-associated Virus (AAV) capsids for effective delivery of gene therapies.
Thrive Here & What We Value- Pioneer in machine learning for blackbox protein design- Values diversity; non-discriminatory policies- NEVY Emerging Company of the Year (2021)- Endpoints 11 Company (2021)- Forbes' America’s Best Startups (2022, 2023)
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